{"id":690,"date":"2025-01-21T16:12:30","date_gmt":"2025-01-21T16:12:30","guid":{"rendered":"https:\/\/www.nordicbioscience.com\/?post_type=biomarker-solutions&#038;p=690"},"modified":"2025-06-04T13:04:09","modified_gmt":"2025-06-04T13:04:09","slug":"psoriasis","status":"publish","type":"biomarker-solution","link":"https:\/\/www.nordicbioscience.com\/biomarker-solution\/dermatology\/psoriasis\/","title":{"rendered":"Psoriasis"},"content":{"rendered":"<section class=\"two-column group white bg-white\">\n        <!-- \n        initialize dynamic classes\n        bg-grey\n        bg-dark\n        lg:flex-row-reverse\n        lg:flex-row\n        -->\n   <div class=\"inner items-center lg:p-8 xl:p-10 p-5 max-w-[1440px] mx-auto flex gap-4 lg:gap-8 xl:gap-10 flex-col lg:flex-row-reverse\">\n        <article class=\"flex flex-col justify-between flex-1 text-column lg:py-8 xl:py-10\">\n            <div class=\"\">\n                <div>\n                                    <h2 class=\"mb-4 font-bold xl:mb-8 title text-m-title-lg xl:text-d-title-md group-[.white]:text-navy group-[.grey]:text-navy group-[.dark]:text-fontlight\">Biomarkers for investigating psoriasis<\/h2>\n                 \n\n                <\/div>\n                <div class=\"wysiwyg mb-8 xl:mb-0 body-text group-[.white]:text-blue group-[.grey]:text-blue group-[.dark]:text-fontlightbody\">\n                    <div class=\"blog-item\">\n<div class=\"container-fluid container-master\">\n<div class=\"block block-mb-negative block-imgs-fg block-grid block-theme-blue block-v-sm text-left fancyfake-item\">\n<div class=\"row mx-0\">\n<div class=\"col-12 col-lg-6 px-0\">\n<div class=\"block-content\">\n<p>Psoriasis is a chronic inflammatory skin disease, characterized by excessive\u00a0tissue remodeling\u00a0and immune cell activity. Psoriasis manifests in scaly reddish plaques on frequently chafed body parts, leading to itching and pain, which may severely affect the patient&#8217;s quality of life.<\/p>\n<p><a href=\"https:\/\/www.nordicbioscience.com\/blog\/extracellular-matric-animation\/\">Tissue-specific biomarkers<\/a>, quantifying and monitoring epidermal damage, dermal damage and immune cell activity, provide key advantages when we want to understand the disease mechanisms.\u00a0Utilizing such biomarkers\u00a0can help monitor disease activity and predict a therapy with greater reliability of response.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n                <\/div>\n                                    <div class=\"mt-8 mb-4 xl:mb-8 links\">\n                        <h3 class=\"mb-2 text-blue group-[.dark]:text-fontlight text-body-sm\">Publications<\/h3>\n                        <ul class=\"flex flex-wrap gap-2\">\n                                                                                                 <li>\n                                        <a class=\"inline-block transition ease-out duration-100 px-[6px] py-1 group-[.dark]:bg-[#434343] group-[.dark]:text-fontlight text-body-sm bg-border rounded-sm text-blue xl:hover:bg-petroleum xl:hover:text-fontlight group-[.dark]:xl:hover:bg-petroleum group-[.dark]:xl:hover:text-fontlight\" href=\"https:\/\/www.nordicbioscience.com\/publication\/?search=%22psoriasis%22\" target=\"_blank\">Psoriasis<\/a>\n                                    <\/li>\n                                                                                    <\/ul>\n                    <\/div>\n                                <\/div>\n                        <\/article>\n        <figure class=\"flex-1 rounded-md -order-1 xl:order-none  xl:rounded-xl overflow-clip media-column shadow-main\">\n            <img decoding=\"async\" class=\"object-cover min-h-full aspect-square\" src=\"https:\/\/www.nordicbioscience.com\/wp-content\/uploads\/2025\/01\/shutterstock-579017614-646dcde10afc8-scaled.webp\" alt=\"\">\n        <\/figure>   \n    <\/div>\n<\/section>\n\n\n<section class=\"two-column group white bg-white\">\n        <!-- \n        initialize dynamic classes\n        bg-grey\n        bg-dark\n        lg:flex-row-reverse\n        lg:flex-row\n        -->\n   <div class=\"inner items-center lg:p-8 xl:p-10 p-5 max-w-[1440px] mx-auto flex gap-4 lg:gap-8 xl:gap-10 flex-col lg:flex-row\">\n        <article class=\"flex flex-col justify-between flex-1 text-column lg:py-8 xl:py-10\">\n            <div class=\"\">\n                <div>\n                                    <h2 class=\"mb-4 font-bold xl:mb-8 title text-m-title-lg xl:text-d-title-md group-[.white]:text-navy group-[.grey]:text-navy group-[.dark]:text-fontlight\">Nordic ProteinFingerPrint Technology\u2122 biomarkers in psoriasis<\/h2>\n                 \n\n                <\/div>\n                <div class=\"wysiwyg mb-8 xl:mb-0 body-text group-[.white]:text-blue group-[.grey]:text-blue group-[.dark]:text-fontlightbody\">\n                    <div class=\"blog-item\">\n<div class=\"container-fluid container-master\">\n<div class=\"block block-mb-negative block-imgs-fg block-grid block-theme-blue block-v-sm text-left fancyfake-item\">\n<div class=\"row mx-0\">\n<div class=\"col-12 col-lg-6 px-0\">\n<div class=\"block-content\">\n<p>Our\u00a0<a href=\"https:\/\/www.nordicbioscience.com\/biomarker-portfolio\/therapeutic-area\/dermatology\/\">dermatology biomarker panels\u00a0<\/a>offer extracellular matrix-based biomarkers, which are fundamentally more different and more specific compared to what\u2019s offered by omics providers. Our <a href=\"https:\/\/www.nordicbioscience.com\/technology\/nordic-proteinfingerprint-technology\/\">Nordic ProteinFingerPrint Technology\u2122<\/a> provides valuable insights into tissue formation, degradation, and resolution, that offer a deeper understanding of pathological processes related to skin diseases.<\/p>\n<p>At the same time, proteomics providers\u2019 wide-range arrays may not offer the same level of specificity. Tissue remodeling and immune cell activity are key features of psoriasis. Quantifying disease activity and remodeling in psoriasis can provide a unique insight into structural and functional changes in the disease pathogenesis.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n                <\/div>\n                                <\/div>\n                                    <div class=\"flex flex-wrap gap-6 xl:mt-8 group dark-button\">\n                                                                                            <a href=\"https:\/\/www.nordicbioscience.com\/biomarker-portfolio\/therapeutic-area\/dermatology\/biomarker-panel\/psoriasis\/\" class=\"group button fill flex items-center font-poppins px-6 py-4 gap-2 transition ease-out duration-200 \n            bg-buttonfill \n            xl:hover:bg-petroleum \n            xl:hover:border-petroleum \n            group-[.dark-button]:text-fontdark \n            group-[.light-button]:text-fontlight\n            xl:group-[.dark-button]:hover:text-fontlight\n            border-2 border-turquoise border-solid rounded-full\n            xl:hover:[&#038;_svg_path]:fill-fontlight\n            group\/button\n            \" target=\"_blank\">\n            Browse our psoriasis biomarkers            <svg width=\"16\" height=\"16\" viewBox=\"0 0 16 16\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                <path class=\"group-[.dark-button]:fill-fontdark group-[.light-button]:fill-fontlight xl:group-hover\/button:!fill-fontlight xl:group-hover\/subtlebutton:!fill-turquoise transition ease-out duration-200\" d=\"M8.0026 2.66699L7.0626 3.60699L10.7826 7.33366L2.66927 7.33366L2.66927 8.66699L10.7826 8.66699L7.05594 12.387L8.0026 13.3337L13.3359 8.00033L8.0026 2.66699Z\" fill=\"#F8F8F8\"\/>\n            <\/svg>\n            <!--group\/button-->\n        <\/a>\n                                                                            <\/div>\n                        <\/article>\n        <figure class=\"flex-1 rounded-md -order-1 xl:order-none  xl:rounded-xl overflow-clip media-column shadow-main\">\n            <img decoding=\"async\" class=\"object-cover min-h-full aspect-square\" src=\"https:\/\/www.nordicbioscience.com\/wp-content\/uploads\/2025\/05\/biomarker-antibody2-nordic-bioscience.webp\" alt=\"\">\n        <\/figure>   \n    <\/div>\n<\/section>\n\n\n<section class=\"two-column group white bg-white\">\n        <!-- \n        initialize dynamic classes\n        bg-grey\n        bg-dark\n        lg:flex-row-reverse\n        lg:flex-row\n        -->\n   <div class=\"inner items-center lg:p-8 xl:p-10 p-5 max-w-[1440px] mx-auto flex gap-4 lg:gap-8 xl:gap-10 flex-col lg:flex-row-reverse\">\n        <article class=\"flex flex-col justify-between flex-1 text-column lg:py-8 xl:py-10\">\n            <div class=\"\">\n                <div>\n                                    <h2 class=\"mb-4 font-bold xl:mb-8 title text-m-title-lg xl:text-d-title-md group-[.white]:text-navy group-[.grey]:text-navy group-[.dark]:text-fontlight\">Biomarker upregulation reveals psoriasis progression<\/h2>\n                 \n\n                <\/div>\n                <div class=\"wysiwyg mb-8 xl:mb-0 body-text group-[.white]:text-blue group-[.grey]:text-blue group-[.dark]:text-fontlightbody\">\n                    <p>A balanced extracellular matrix (ECM) is necessary to preserve skin integrity and tissue homeostasis. Several ECM components of the dermis, epidermis, and epidermal basement membrane, reflecting the individual skin compartments are remodeled during psoriasis progression.<\/p>\n<p>Biomarkers related to psoriasis pathogenesis are crucial for use in clinical trials, but also to advance the knowledge of the biological complexity and heterogeneity behind psoriasis.<\/p>\n<p>The biomarkers utility in the disease is depicted by\u00a0<a href=\"https:\/\/www.nordicbioscience.com\/biomarker\/pro-c3\/\" target=\"_blank\" rel=\"noreferrer noopener\" data-type=\"biomarker\" data-id=\"1083\">PRO-C3 (nordicPRO-C3\u2122)<\/a> (Activated dermal fibroblasts; Formation of type III collagen) and <a href=\"https:\/\/www.nordicbioscience.com\/biomarker\/cpa9-hne\/\" data-type=\"biomarker\" data-id=\"1023\">CPa9-HNE<\/a> (nordicCPa9-HNE\u2122, Neutrophil activity; S100A9 degraded by human neutrophil elastase), in Figure 1. Both biomarkers are upregulated in patients with psoriasis.<\/p>\n                <\/div>\n                                <\/div>\n                        <\/article>\n        <figure class=\"flex-1 rounded-md -order-1 xl:order-none  xl:rounded-xl overflow-clip media-column shadow-main\">\n            <img decoding=\"async\" class=\"object-cover min-h-full aspect-square\" src=\"https:\/\/www.nordicbioscience.com\/wp-content\/uploads\/2025\/01\/healthy-_1_.webp\" alt=\"\">\n        <\/figure>   \n    <\/div>\n<\/section>\n\n\n<section class=\"two-column group white bg-white\">\n        <!-- \n        initialize dynamic classes\n        bg-grey\n        bg-dark\n        lg:flex-row-reverse\n        lg:flex-row\n        -->\n   <div class=\"inner items-center lg:p-8 xl:p-10 p-5 max-w-[1440px] mx-auto flex gap-4 lg:gap-8 xl:gap-10 flex-col lg:flex-row\">\n        <article class=\"flex flex-col justify-between flex-1 text-column lg:py-8 xl:py-10\">\n            <div class=\"\">\n                <div>\n                                    <h2 class=\"mb-4 font-bold xl:mb-8 title text-m-title-lg xl:text-d-title-md group-[.white]:text-navy group-[.grey]:text-navy group-[.dark]:text-fontlight\">Nordic Bioscience can quantify the different layers of the skin<\/h2>\n                 \n\n                <\/div>\n                <div class=\"wysiwyg mb-8 xl:mb-0 body-text group-[.white]:text-blue group-[.grey]:text-blue group-[.dark]:text-fontlightbody\">\n                    <p>The skin is the largest organ of the human body, and consists of three different layers; epidermis, dermis and subcutis. These three layers have distinct tissue architectures and functions.<\/p>\n<p>Skin functions are dependent on a complex composition of <a href=\"https:\/\/www.nordicbioscience.com\/blog\/extracellular-matric-animation\/\">extracellular matrix (ECM) proteins<\/a>. The ECM of the skin can be divided into the epidermal ECM, epidermal basement membrane and the papillary\/reticular ECM. The major ECM components of the skin are collagens, which are located in the different tissue compartments to maintain tissue architecture.<\/p>\n<p>The\u00a0<a href=\"https:\/\/www.nordicbioscience.com\/technology\/nordic-proteinfingerprint-technology\/\" data-type=\"page\" data-id=\"2167\">Nordic ProteinFingerPrint Technology\u2122<\/a> allows for the quantification of the different layers of the skin, and also the quantification of immune cell activity involved in different pathologies (mast cells, <a href=\"https:\/\/www.nordicbioscience.com\/technology\/cpa9-hne-nordiccpa9-hne-the-serum-calprotectin\/\">neutrophils<\/a>, and macrophages).<\/p>\n                <\/div>\n                                <\/div>\n                                    <div class=\"flex flex-wrap gap-6 xl:mt-8 group dark-button\">\n                                                                                            <a href=\"https:\/\/www.nordicbioscience.com\/biomarker-solution\/skin-diseases\/\" class=\"group button fill flex items-center font-poppins px-6 py-4 gap-2 transition ease-out duration-200 \n            bg-buttonfill \n            xl:hover:bg-petroleum \n            xl:hover:border-petroleum \n            group-[.dark-button]:text-fontdark \n            group-[.light-button]:text-fontlight\n            xl:group-[.dark-button]:hover:text-fontlight\n            border-2 border-turquoise border-solid rounded-full\n            xl:hover:[&#038;_svg_path]:fill-fontlight\n            group\/button\n            \" target=\"\">\n            Biomarkers for dermatology indications             <svg width=\"16\" height=\"16\" viewBox=\"0 0 16 16\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                <path class=\"group-[.dark-button]:fill-fontdark group-[.light-button]:fill-fontlight xl:group-hover\/button:!fill-fontlight xl:group-hover\/subtlebutton:!fill-turquoise transition ease-out duration-200\" d=\"M8.0026 2.66699L7.0626 3.60699L10.7826 7.33366L2.66927 7.33366L2.66927 8.66699L10.7826 8.66699L7.05594 12.387L8.0026 13.3337L13.3359 8.00033L8.0026 2.66699Z\" fill=\"#F8F8F8\"\/>\n            <\/svg>\n            <!--group\/button-->\n        <\/a>\n                                                                            <\/div>\n                        <\/article>\n        <figure class=\"flex-1 rounded-md -order-1 xl:order-none  xl:rounded-xl overflow-clip media-column shadow-main\">\n            <img decoding=\"async\" class=\"object-cover min-h-full aspect-square\" src=\"https:\/\/www.nordicbioscience.com\/wp-content\/uploads\/2025\/01\/skinlayers-webp.webp\" alt=\"\">\n        <\/figure>   \n    <\/div>\n<\/section>\n\n\n\n<div style=\"height:var(--wp--preset--spacing--40)\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<section class=\"accordion-block\">\n    <div class=\"inner xl:p-10 lg:p-8 lg:pb-0 xl:pb-0 p-5 pb-0 max-w-[1440px] mx-auto\">\n        <div>\n                    <h2 class=\"mb-4 font-bold xl:mb-8 title text-m-title-lg xl:text-d-title-lg text-navy\">About psorisasis<\/h2>\n         \n        <\/div>\n            <ul class=\"accordion\">\n                            <!-- Accordion Item -->\n                <li>\n                    <button data-index=\"1\" \n                            class=\"flex items-center justify-between w-full py-5 font-bold text-m-title-sm xl:text-d-title-sm accordion-button text-navy\">\n                        <span class=\"text-start\">What is psorisasis?<\/span>\n                        <span id=\"icon-1\" class=\"transition-transform duration-300 text-turquoise\">\n                            <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 16 16\" fill=\"currentColor\" class=\"w-4 h-4 xl:w-6 xl:h-6\">\n                                <path d=\"M8.75 3.75a.75.75 0 0 0-1.5 0v3.5h-3.5a.75.75 0 0 0 0 1.5h3.5v3.5a.75.75 0 0 0 1.5 0v-3.5h3.5a.75.75 0 0 0 0-1.5h-3.5v-3.5Z\" \/>\n                            <\/svg>\n                        <\/span>\n                    <\/button>\n                    <div id=\"content-1\" class=\"overflow-hidden transition-all duration-300 ease-in-out accordion-content max-h-0\">\n                        <div class=\"pb-5 text-sm max-w-[600px] text-blue\">\n                            <p><span class=\"NormalTextRun SCXW70577717 BCX8\">Psoriasis is a comm<\/span><span class=\"NormalTextRun SCXW70577717 BCX8\">on, chronic, immune-mediated disease manifested in the skin, affecting 2-3% of the population. <\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span class=\"NormalTextRun SCXW70577717 BCX8\">It appears in early adulthood and is a lifelong condition. Up to 90% of all psoriasis patients have plaque psoriasis, which is characterized by \u201cplaques\u201d of the\u00a0skin, that are mainly found on the scalp, knees, elbows, trunk, and limbs causing itching and pain.<\/span><\/p>\n<p>&nbsp;<\/p>\n                        <\/div>\n                    <\/div>\n                <\/li>\n                            <!-- Accordion Item -->\n                <li>\n                    <button data-index=\"2\" \n                            class=\"flex items-center justify-between w-full py-5 font-bold text-m-title-sm xl:text-d-title-sm accordion-button text-navy\">\n                        <span class=\"text-start\">How is psoriasis diagnosed and treated?<\/span>\n                        <span id=\"icon-2\" class=\"transition-transform duration-300 text-turquoise\">\n                            <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 16 16\" fill=\"currentColor\" class=\"w-4 h-4 xl:w-6 xl:h-6\">\n                                <path d=\"M8.75 3.75a.75.75 0 0 0-1.5 0v3.5h-3.5a.75.75 0 0 0 0 1.5h3.5v3.5a.75.75 0 0 0 1.5 0v-3.5h3.5a.75.75 0 0 0 0-1.5h-3.5v-3.5Z\" \/>\n                            <\/svg>\n                        <\/span>\n                    <\/button>\n                    <div id=\"content-2\" class=\"overflow-hidden transition-all duration-300 ease-in-out accordion-content max-h-0\">\n                        <div class=\"pb-5 text-sm max-w-[600px] text-blue\">\n                            <p><span class=\"NormalTextRun SCXW70577717 BCX8\">Psoriasis is diagnosed by medical examination and can upon diagnosis be treated accordingly.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span class=\"NormalTextRun SCXW70577717 BCX8\"> The first in-line treatments include topical corticosteroids, while severe cases may receive biologics and oral treatments.<\/span><\/p>\n                        <\/div>\n                    <\/div>\n                <\/li>\n                            <!-- Accordion Item -->\n                <li>\n                    <button data-index=\"3\" \n                            class=\"flex items-center justify-between w-full py-5 font-bold text-m-title-sm xl:text-d-title-sm accordion-button text-navy\">\n                        <span class=\"text-start\">What role do biomarkers play in psoriasis?<\/span>\n                        <span id=\"icon-3\" class=\"transition-transform duration-300 text-turquoise\">\n                            <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 16 16\" fill=\"currentColor\" class=\"w-4 h-4 xl:w-6 xl:h-6\">\n                                <path d=\"M8.75 3.75a.75.75 0 0 0-1.5 0v3.5h-3.5a.75.75 0 0 0 0 1.5h3.5v3.5a.75.75 0 0 0 1.5 0v-3.5h3.5a.75.75 0 0 0 0-1.5h-3.5v-3.5Z\" \/>\n                            <\/svg>\n                        <\/span>\n                    <\/button>\n                    <div id=\"content-3\" class=\"overflow-hidden transition-all duration-300 ease-in-out accordion-content max-h-0\">\n                        <div class=\"pb-5 text-sm max-w-[600px] text-blue\">\n                            <p><span class=\"NormalTextRun SCXW70577717 BCX8\"><span class=\"TextRun BCX8 SCXW63148528\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX8 SCXW63148528\">The main component of the skin is collagens, which are remodeled as a part of the normal homeostasis of the skin. <\/span><\/span><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span class=\"NormalTextRun SCXW70577717 BCX8\"><span class=\"TextRun BCX8 SCXW63148528\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX8 SCXW63148528\">I<\/span><\/span><\/span><span class=\"NormalTextRun SCXW70577717 BCX8\"><span class=\"TextRun BCX8 SCXW63148528\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX8 SCXW63148528\">n psoriasis, there is an imbalance of tissue build-up and tissue breakdown, resulting in a net degradation of the tissue.<\/span><span class=\"NormalTextRun BCX8 SCXW63148528\">\u00a0<\/span><\/span><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span class=\"NormalTextRun SCXW70577717 BCX8\"><span class=\"TextRun Highlight BCX8 SCXW63148528\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX8 SCXW63148528\">Nordic ProteinFingerPrint\u2122 biomarkers can quantify skin tissue turnover directly in a serum sample and serve as a liquid biopsy.<\/span><\/span><\/span><\/p>\n                        <\/div>\n                    <\/div>\n                <\/li>\n                            <!-- Accordion Item -->\n                <li>\n                    <button data-index=\"4\" \n                            class=\"flex items-center justify-between w-full py-5 font-bold text-m-title-sm xl:text-d-title-sm accordion-button text-navy\">\n                        <span class=\"text-start\"><\/span>\n                        <span id=\"icon-4\" class=\"transition-transform duration-300 text-turquoise\">\n                            <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 16 16\" fill=\"currentColor\" class=\"w-4 h-4 xl:w-6 xl:h-6\">\n                                <path d=\"M8.75 3.75a.75.75 0 0 0-1.5 0v3.5h-3.5a.75.75 0 0 0 0 1.5h3.5v3.5a.75.75 0 0 0 1.5 0v-3.5h3.5a.75.75 0 0 0 0-1.5h-3.5v-3.5Z\" \/>\n                            <\/svg>\n                        <\/span>\n                    <\/button>\n                    <div id=\"content-4\" class=\"overflow-hidden transition-all duration-300 ease-in-out accordion-content max-h-0\">\n                        <div class=\"pb-5 text-sm max-w-[600px] text-blue\">\n                                                    <\/div>\n                    <\/div>\n                <\/li>\n                    <\/ul>\n    \n    <\/div>\n<\/section>\n\n\n\n<div style=\"height:var(--wp--preset--spacing--50)\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<section class=\"two-column group white bg-white\">\n        <!-- \n        initialize dynamic classes\n        bg-greybg\n        bg-dark\n        xl:flex-row-reverse\n        xl:flex-row\n        -->\n   <div class=\"inner xl:p-10 lg:p-8 p-5 max-w-[1440px] mx-auto flex gap-4 xl:gap-10 flex-col xl:flex-row-reverse\">\n        <article class=\"flex flex-col justify-between flex-1 text-column\">\n            <div class=\"\">\n                <div>\n                                    <h2 class=\"mb-4 font-bold xl:mb-8 title text-m-title-lg xl:text-d-title-lg group-[.white]:text-navy group-[.grey]:text-navy group-[.dark]:text-fontlight\">Get in touch<\/h2>\n                 \n\n                <\/div>\n                <div class=\"xl:mb-0 body-text group-[.white]:text-blue group-[.grey]:text-blue group-[.dark]:text-fontlightbody\">\n                    <div class=\"mb-10\">\n                        <div class=\"mb-4\">\n                            Are you interested in exploring collaboration possibilities?\u2028Enter your information in the form and a representative will contact 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